منابع مشابه
When more is not more
oosting the function of a learning protein jams the brain with too much information, according to Ype Elgersma (Erasmus MC, Rotterdam, Netherlands), Alcino Silva (University of California, Los Angeles, CA), and colleagues. The result is a cautionary tale for those seeking to develop learning drugs. The team created mice lacking two inhibitory phosphorylation sites on CaMKII. Wild-type CaMKII is...
متن کاملWhen Less is More
engine and airframe manufacturers for decades have cited the direct relationship between engine wear and high exhaust gas temperature (EGT) in recommending that operators use less than maximum takeoff thrust whenever possible. While the cost benefits of reduced-thrust takeoffs are thoroughly documented, the safety benefits are not as well understood. Thus, there is a common perception that usin...
متن کاملWhen more is better
Nutrition support of critically ill patients with sepsis is one of the most debated issues among intensivists. The latest international sepsis guidelines recommend the prescription of a low volume of feeds through gastric or intestinal enteral nutrition (EN) for 7 days after admission to the ICU. The data to support such recommendations are scarce, and large trials are needed to clarify this is...
متن کاملWhen Less is More.
minimum level. Sometimes more really is more, and less really is less. But often, less is more. If all this piece does is open up the question of whether less is more —if all it does is remind the reader that this is a question, and that our answers to it have important repercussions— then it will have served its purpose. Many ethicists in the ancient tradition argued that human lives could be ...
متن کاملGiant Orbitoethmoidal Osteoma: When an Open Surgical Approach Is Required
Giant orbitoethmoidal osteoma in children is considered to be rare. This type of pathology can be associated with significant disfiguring proptosis and limitation of eye movement. Here, we report on a child who presented with a giant orbitoethmoidal osteoma that was removed through an orbitofrontal approach. The cosmetic result was excellent and evident immediately after surgery. A review of th...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery Cases and Innovative Techniques
سال: 2021
ISSN: 2468-4287
DOI: 10.1016/j.jvscit.2021.04.028